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Biomechanics of the Cervical Plate for Posterior Cervical Fusion in Cervical Osteomyelitis: A Mechanic Device Study.
Cervical bone graft substitutes (CBS) may be used for stabilization of the cervical spine in patients with infected vertebral bone grafts. CBS provide the structure to promote bone union. In this study, we investigated the biomechanical stability of a new CBS-bone interface device in a cervical osteomyelitis model. We hypothesized that the device would be resistant to bi-directional loading of the spine. Adult pigs (n = 24) were used to create six C2-C7 osteomyelitis models. In each model, one defect was stabilized with a biodegradable CBS, and the other with a bone plate. All implants were stabilized in the bone grafts using a cervical transpedicular plate and a wire-mesh construct. At 6 weeks postoperatively, the intact cervical spine and the stabilized spine were loaded bi-directionally in axial compression. Specimens were loaded at a constant compressive rate of 0.6 MPa/s until failure occurred. The average compressive failure load of the C2-C7 fusion construct decreased from 1665.9 ± 207.3 N to 1191.2 ± 123.0 N when a CBS was inserted, p Mountain Bike Trail Report 2015

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